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Holt–Winters models are used for forecasting data with changing trends and seasonal correlation, using triple exponential smoothing to account for three parameters: mean values (level), trend over time and seasonality
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Estos efectos se relacionan con la activación del receptor del GLP-1 (GLP-1R), que se expresa en las células beta, el riñón, el hígado, el miocardio, adipocitos, intestino e hipotálamo
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